Moderate to severe hepatic steatosis on computerized tomography imaging: Prevalence in obese Pacific Islanders and Asians

Autor: Bradley James Ikaika Thomas, Melia Nicole Takakusagi, Ruixue Zhang, Hyo‐Chun Yoon
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: JGH Open, Vol 7, Iss 10, Pp 698-701 (2023)
Druh dokumentu: article
ISSN: 2397-9070
DOI: 10.1002/jgh3.12968
Popis: Abstract Background and Aim Hepatic steatosis (HS) is common worldwide, but there is little data on the prevalence of HS in Pacific Islanders (PIs) and Asians within the United States. Our aim was to compare prevalence of HS in obese 18–50‐year‐olds of Asian and PI ethnicity who underwent computerized tomography (CT). Methods We performed a retrospective analysis of all members of an integrated healthcare system who self‐identified as Asian or PI, were between the ages of 18 and 50 years, had a body mass index (BMI) ≥ 30, and underwent a CT scan that included the liver during 2021, resulting in 748 subjects. Imaging was analyzed using a method sensitive and specific for moderate to severe HS. Additionally, multiple binary logistic regression was performed to explore the relationship between HS and HbA1c, BMI, and age. Results Of the 748 patients, 311 (41.6%) had HS. We found no significant difference in the prevalence of HS between Asians and PIs (χ21 = 1.3, P = 0.25), between Asian and PI men (χ21 = 2.8, P = 0.096), or between Asian and PI women (χ21 = 0.053, P = 0.82). Higher odds of HS was associated with increasing BMI (OR = 1.08; 95% CI: 1.06–1.11; P
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