Seizures after intravenous tramadol given as premedication

Autor: Lalit Kumar Raiger, Udita Naithani, Sonali Bhatia, Sandeep Singh Chauhan
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Indian Journal of Anaesthesia, Vol 56, Iss 1, Pp 55-57 (2012)
Druh dokumentu: article
ISSN: 0019-5049
DOI: 10.4103/0019-5049.93345
Popis: A 35-year-old, 50-kg female with a history of epilepsy was scheduled for elective breast surgery (fibroadenoma) under general anaesthesia. She was given glycopyrrolate 0.2 mg, ondansetron 4 mg and tramadol 100 mg i.v. as premedication. Within 5 min, she had an acute episode of generalised tonic-clonic seizure that was successfully treated with 75 mg thiopentone i.v. and after 30 min, she was given general anaesthesia with endotracheal intubation. Surgery, intra-operative period, extubation and post-operative period were uneventful. We conclude that tramadol may provoke seizures in patients with epilepsy even within the recommended dose range.
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