Influence of allogeneic mesenchymal stem cells on leukemic cells in vitro sensitivity to antileukemic drugs

Autor:	O. S. Tatarinova, E. Yu. Osipova, S. A. Rumyantsev
Jazyk:	ruština
Rok vydání:	2022
Předmět:	mesenchymal stem cells antileukemic drug sensitivity leukemic cells spontaneous apoptosis cytarabine-induced apoptosis Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Онкогематология, Vol 0, Iss 4, Pp 33-38 (2022)
Druh dokumentu:	article
ISSN:	1818-8346 2413-4023
Popis:	In present study influence of allogeneic bone marrow mesenchymal stem cells (MSC) on patients’ leukemic cells is investigated. Influence on in vitro sensitivity to antileukemic drugs and spontaneous and cytarabine-induced apoptosis of leukemic cells was studied. It has`been shown that MSC reduce myeloid leukemic cells sensitivity to daunorubicine. However, MSC did not statistically significant influence on spontaneous and cytarabine-induced apoptosis of leukemic cells.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0c222caa76184c708dc7462427d0ddbd Zobrazit plný text záznamu View record in DOAJ