Impact of Hypoglycemia on Health-Related Quality of Life among Type 2 Diabetes: A Cross-Sectional Study in Thailand

Autor: Thongchai Pratipanawatr, Bancha Satirapoj, Boonsong Ongphiphadhanakul, Sompongse Suwanwalaikorn, Wannee Nitiyanant
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of Diabetes Research, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 2314-6745
2314-6753
DOI: 10.1155/2019/5903820
Popis: Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases. Patients are generally advised lifestyle changes with antihyperglycemic agents prescribed. The major drawback of prescribing antihyperglycemic agents is the risk of hypoglycemia which subsequently impacts on health-related quality of life (HRQoL). This study is aimed at examining association between previous history of hypoglycemia and HRQoL. The study was a multicenter cross-sectional study, conducted from February 2013 to March 2015 at 5 tertiary care hospitals in Thailand (Srinagarind, Phramongkutklao, Ramathibodi, King Chulalongkorn Memorial, and Siriraj hospitals). The study population were males or females diagnosed with type 2 DM according to ADA criteria, 30 years of age or older, who had been treated with sulfonylurea (SU) monotherapy or SU and metformin combination for at least 6 months. Prespecified medical factors were extracted from medical records 12 months prior to patients’ enrolment. The experience of hypoglycemia questionnaire was used to collect and measure severity of hypoglycemia experienced during the previous 6 months. HRQoL was assessed using the 3-level version of EuroQol-5-dimension (EQ-5D-3L) and visual analogue scale (EQ-VAS) questionnaires. Of 659 eligible patients surveyed, 202 patients (30.65%) had experienced symptoms of hypoglycemia. HRQoL was significantly lower among patients reporting at least one of hypoglycemic symptoms, measured by EQ-VAS scores (mean±SD; 73.66±13.18, 73.56±15.10, or 68.93±14.76 vs. 77.01±13.02, one-way ANOVA; p=0.006) and EQ-5D-3L index scores (0.62±0.47, 0.68±0.38, or 0.58±0.51 vs. 0.79±0.31, one-way ANOVA; p
Databáze: Directory of Open Access Journals
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje