A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins

Autor: Ilka Erven, Elena Abraham, Thomas Hermanns, Ulrich Baumann, Kay Hofmann
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-35244-y
Popis: The authors describe the VTD-deubiquitinases, a new eukaryotic enzyme family that is distantly related to herpesviral large tegument proteins. Structures of two family members with different linkage preferences allow insights into the mechanism and chain-specificity of this unusual deubiquitinase class.
Databáze: Directory of Open Access Journals