The prognostic value of lymphocyte-to-monocyte ratio in retinopathy of prematurity

Autor: Yu-Xiang Hu, Xiao-Xuan Xu, Yi Shao, Gao-Le Yuan, Feng Mei, Quan Zhou, Yi Cheng, Jun Wang, Xiao-Rong Wu
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: International Journal of Ophthalmology, Vol 10, Iss 11, Pp 1716-1721 (2017)
Druh dokumentu: article
ISSN: 2222-3959
2227-4898
DOI: 10.18240/ijo.2017.11.13
Popis: AIM: To evaluate the associations between development of retinopathy of prematurity (ROP) and serum lymphocyte-to-monocyte ratio (LMR), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR). METHODS: A retrospective cohort study was performed, involving infants who were screened for ROP from January 2015 to December 2015. Preterm newborns of ≤32 gestational weeks with ROP were enrolled as the observation group, and non-ROP infants were enrolled as the control group, whose complete blood cell were measured within the first 24h of life. The levels of NLR, LMR and PLR were determined in all groups. The data obtained were analyzed using univariate and multivariate logistic regression analysis. RESULTS: In this study, 40 cases of ROP were enrolled and 40 cases of non-ROP as controls. The LMR levels were significantly higher (P
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