Increased levels of chitotriosidase in a patient with Alagille syndrome: association or coincidence?
| Autor: | Bruna L. Diniz, Maiara A. Floriani, Maria Angélica T. Ferreira, João Francisco O. Gonzales, Nathan H. Lisboa, André Ricardo Jakimiu, Janaina Yacy H. Ferreira, Rafael Fabiano M. Rosa, Paulo Ricardo G. Zen |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: | |
| Zdroj: | Jornal Brasileiro de Patologia e Medicina Laboratorial, Vol 54, Iss 1, Pp 37-39 (2018) |
| Druh dokumentu: | article |
| ISSN: | 1678-4774 1676-2444 80151434 |
| DOI: | 10.5935/1676-2444.20180008 |
| Popis: | ABSTRACT We describe a case of a patient with Alagille syndrome (AS) presenting an increased level of the enzyme chitotriosidase (ChT), evaluating factors that could justify the relationship between AS and ChT. He was a male patient with cholestatic jaundice, facial dysmorphia and congenital heart disease who presented a brief septicemia. He underwent liver biopsy and analyses for inborn errors of metabolism that respectively showed ductopenia and increased levels of ChT. This increase could be potentially explained by inflammatory and infectious processes, or even by AS itself. |
| Databáze: | Directory of Open Access Journals |
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