| Autor: |
Manuela Burghelea, Jinane Bakkali Tahiri, Jennifer Dhont, Martin Kyndt, Akos Gulyban, Juliane Szkitsak, Evelien Bogaert, Dirk van Gestel, Nick Reynaert |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Physics and Imaging in Radiation Oncology, Vol 28, Iss , Pp 100479- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2405-6316 |
| DOI: |
10.1016/j.phro.2023.100479 |
| Popis: |
Background and purpose: 4D Computed Tomography (4DCT) technology captures the location and movement of tumors and nearby organs at risk over time. In this study, a multi-institutional multi-vendor 4DCT audit was initiated to assess the accuracy of current imaging protocols. Materials and methods: Twelve centers, including thirteen scanners performed a 4DCT acquisition of a dynamic thorax phantom using the institution’s own protocol with the in-house breathing monitoring system. Five regular and three irregular breathing patterns were used. Image acquisition and reconstruction were followed by automated image analysis with our in-house developed 4DCT QA program (QAMotion). CT number accuracy, volume deviation, amplitude deviation, and spatial integrity were assessed per pattern using both the segmented volumes and line profiles. Results: Regular breathing curves showed relatively accurate results across all institutions, with mean volume and CT number deviations and median amplitude deviation below 2%, 5 HU and 2 mm, respectively. Results obtained for irregular patterns showed more variation across the institutions. Volume and CT number deviations co-occurred with a blurring of the sphere, interpolation, or double-structure artifacts that were confirmed through the line profiles. For some of the irregular patterns, amplitude deviations up to 6 mm were observed. Maximum Intensity Projection (MaxIP) correctly captured the applied motion amplitude with deviations across all institutions within 2 mm except for double amplitude pattern. Conclusions: All centers invited to participate in the audit responded positively, highlighting the need for a comprehensive yet easy-to-execute 4DCT quality assurance program. The largest variances between the results from one institution to another confirmed that a standardized 4DCT audit is warranted. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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