Effect of Gliclazide or Gliclazide plus Metformin Combination on Glycemic Control in Patients with T2DM in India: A Real-World, Retrospective, Longitudinal, Observational Study from Electronic Medical Records

Autor: Nareen Krishna Polavarapu, Ravindra Kale, Bipin Sethi, R. K. Sahay, Uday Phadke, Santosh Ramakrishnan, Amey Mane, Suyog Mehta, Snehal Shah
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Drugs - Real World Outcomes, Vol 7, Iss 4, Pp 271-279 (2020)
Druh dokumentu: article
ISSN: 2199-1154
2198-9788
54998832
DOI: 10.1007/s40801-020-00206-7
Popis: Abstract Background The efficacy of gliclazide has been reported in clinical trials in India. However, real-world data on the effectiveness of gliclazide in India is unavailable. Objective To provide real-world evidence regarding the effectiveness of gliclazide or gliclazide + metformin fixed-dose combination or separate medications, used either as monotherapy or as the latest add-on to other antihyperglycemic agents in reducing glycated hemoglobin (HbA1c) levels in Indian patients with type 2 diabetes mellitus (T2DM). Methods Electronic medical record data of adult patients who were diagnosed with T2DM who were newly initiated on or had been prescribed gliclazide or gliclazide + metformin combination for 7% was − 0.8% (− 1.26, − 0.34) in gliclazide only group; − 1.6% (− 1.89, − 1.31; p
Databáze: Directory of Open Access Journals
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