Cladribine chemotherapy of multifocal, multisystemic form of Rosai–Dorfman disease: literature review and case report
| Autor: | V. G. Potapenko, D. S. Abramov, V. V. Baykov, T. L. Grigorieva, M. S. Selinkina, L. O. Nikolskaya, J.-F. Emile |
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| Jazyk: | ruština |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Онкогематология, Vol 19, Iss 2, Pp 46-55 (2024) |
| Druh dokumentu: | article |
| ISSN: | 1818-8346 2413-4023 |
| DOI: | 10.17650/1818-8346-2024-19-2-46-55 |
| Popis: | Rosai–Dorfman disease is the most frequent variant of non-Langerhans cell histiocytosis. Local forms can be resected or irradiated. If the process involves multiple organs, systemic chemotherapy can cure some patients. This article includes literature review and a case report of a 34-year-old patient with multifocal, multisystemic form of Rosai–Dorfman disease with bone and pleural involvement. The diagnosis was based on histological, immunohistochemical, and molecular studies of tumor tissue. Since November 2021, 6 courses of chemotherapy with cladribine and 8 infusions of zolendronic acid were carried out with achievement of durable remission. The tolerance was acceptable. |
| Databáze: | Directory of Open Access Journals |
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