Pitfalls in Diagnosing Thrombotic Thrombocytopenic Purpura in Sickle Cell Disease

Autor:	Dimitris A. Tsitsikas, Diana Mihalca, John Hall, Jori E. May, Radhika Gangaraju, Marisa B. Marques, Marie Scully
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	sickle cell disease thrombotic thrombocytopenic purpura fat embolism syndrome therapeutic plasma exchange Medicine
Zdroj:	Journal of Clinical Medicine, Vol 11, Iss 22, p 6676 (2022)
Druh dokumentu:	article
ISSN:	11226676 2077-0383
DOI:	10.3390/jcm11226676
Popis:	Thrombotic thrombocytopenia purpura is characterised by microangiopathic haemolytic anaemia and red cell fragmentation on the peripheral smear, neurological involvement and thrombocytopenia. Diagnosis in the context of sickle cell disease can be challenging due to the inherent haemolytic state and the multitude of other associated complications of the latter. Specifically, fat embolism syndrome characterised by respiratory failure, neurological impairment and thrombocytopenia can be misdiagnosed this way. Confirmation of a diagnosis of thrombotic thrombocytopenic purpura requires demonstration of very low levels (
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0bc081c851d64054a35d6284f97776b0 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.