| Autor: |
Kelsey L. Corrigan, Bryce B. Reeve, John M. Salsman, Elizabeth J. Siembida, Grace L. Smith, Maria C. Swartz, Kamaria L. Lee, Faraz Afridi, Lauren M. Andring, Andrew J. Bishop, Jillian R. Gunther, J. Andrew Livingston, Susan K. Peterson, Michael Roth |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Cancer Medicine, Vol 12, Iss 13, Pp 14157-14170 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2045-7634 |
| DOI: |
10.1002/cam4.6082 |
| Popis: |
Abstract Background Radiation therapy (RT) is a common treatment for adolescents and young adults (AYAs, 15–39 years old) with cancer; however, it may cause toxicities that affect health‐related quality‐of‐life (HRQOL). Thus, we assessed HRQOL in AYAs before, during, and after RT. Methods We identified 265 AYAs who completed HRQOL PROMIS® surveys before (n = 87), during (n = 84), or after (n = 94) RT. Higher PROMIS® score represents more of the concept. Mean scores were compared to the general US population and minimally important differences (MIDs) were used to evaluate the impact of cancer on HRQOL. Linear regression modeling was used to evaluate the effect of clinical and demographic factors on PROMIS scores. Results Median [IQR] age was 26 [20–31] years. Cancer types varied; most had sarcoma (26%) or CNS malignancy (23%). Compared to the general US population, the before RT cohort had worse anxiety (mean score 55.2 vs. 50, MID 3, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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