Association of sleep apnoea risk and aortic enlargement in Marfan syndrome

Autor: Harry Dietz, Mudiaga Sowho, Gretchen MacCarrick, Jonathan Jun, Alan R Schwartz, Enid R Neptune
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMJ Open Respiratory Research, Vol 8, Iss 1 (2021)
Druh dokumentu: article
ISSN: 2052-4439
DOI: 10.1136/bmjresp-2021-000942
Popis: Background Marfan syndrome (MFS) is a connective tissue disorder characterised by complex aortic pathology and a high prevalence of obstructive sleep apnoea (OSA). OSA produces intrathoracic transmural stresses that may accelerate aortic injury. The current study was designed to examine the associations between OSA risk and markers of aortic enlargement in MFS.Method Consecutive patients with MFS were recruited at Johns Hopkins if they completed a STOP-BANG survey. Composite survey scores were categorised into those with low OSA risk (STOP-BANG
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