Tween-20 transiently changes the surface morphology of PK-15 cells and improves PCV2 infection

Autor:	Tao Hua, Xuehua Zhang, Bo Tang, Chen Chang, Guoyang Liu, Lei Feng, Yang Yu, Daohua Zhang, Jibo Hou
Jazyk:	angličtina
Rok vydání:	2018
Předmět:	Nonionic surfactant Tween-20 PCV2 Viral infection Cellular morphologic change Veterinary medicine SF600-1100
Zdroj:	BMC Veterinary Research, Vol 14, Iss 1, Pp 1-8 (2018)
Druh dokumentu:	article
ISSN:	1746-6148
DOI:	10.1186/s12917-018-1457-5
Popis:	Abstract Background Low concentrations of nonionic surfactants can change the physical properties of cell membranes, and thus and in turn increase drug permeability. Porcine circovirus 2 (PCV2) is an extremely slow-growing virus, and PCV2 infection of PK-15 cells yields very low viral titers. The present study investigates the effect of various nonionic surfactants, namely, Tween-20, Tween-28, Tween-40, Tween-80, Brij-30, Brij-35, NP-40, and Triton X-100 on PCV2 infection and yield in PK-15 cells. Result Significantly increased PCV2 infection was observed in cells treated with Tween-20 compared to those treated with Tween-28, Tween-40, Brij-30, Brij-35, NP-40, and Triton X-100 (p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0b6c8380002142cfa0b1ba5a5d211a57 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.