Disseminated Mycobacterium scrofulaceum Infection in a Patient with Anti-Interferon-γ Autoantibodies: A Case Report and Review of the Literature
| Autor: | Surachai Chaononghin, Suttichai Visuttichaikit, Anucha Apisarnthanarak, Thana Khawcharoenporn |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | International Journal of Mycobacteriology, Vol 9, Iss 1, Pp 91-94 (2020) |
| Druh dokumentu: | article |
| ISSN: | 2212-5531 2212-554X |
| DOI: | 10.4103/ijmy.ijmy_182_19 |
| Popis: | Mycobacterium scrofulaceum is an environmental mycobacterial species rarely reported to cause disseminated infection in adults. We report the case of a disseminated M. scrofulaceum infection in a 55-year-old nonhuman immunodeficiency virus-infected Thai man with anti-interferon-γ autoantibodies. The clinical signs of the infection improved after the induction regimen with amikacin, rifampicin, ethambutol, and clarithromycin, followed by the consolidation regimen with ethambutol, clarithromycin, and trimethoprim/sulfamethoxazole. Our review of previous reported cases of this infection indicates its association with immune deficiency, complex treatment, and a high rate of unfavorable outcomes. |
| Databáze: | Directory of Open Access Journals |
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