The Association Between Persistent White-Matter Abnormalities and Repeat Injury After Sport-Related Concussion

Autor: Benjamin L. Brett, Yu-Chien Wu, Sourajit M. Mustafi, Andrew J. Saykin, Kevin M. Koch, Andrew S. Nencka, Christopher C. Giza, Joshua Goldman, Kevin M. Guskiewicz, Jason P. Mihalik, Stefan M. Duma, Steven P. Broglio, Thomas W. McAllister, Michael A. McCrea, Timothy B. Meier
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Frontiers in Neurology, Vol 10 (2020)
Druh dokumentu: article
ISSN: 1664-2295
DOI: 10.3389/fneur.2019.01345
Popis: Objective: A recent systematic review determined that the physiological effects of concussion may persist beyond clinical recovery. Preclinical models suggest that ongoing physiological effects are accompanied by increased cerebral vulnerability that is associated with risk for subsequent, more severe injury. This study examined the association between signal alterations on diffusion tensor imaging following clinical recovery of sport-related concussion in athletes with and without a subsequent second concussion.Methods: Average mean diffusivity (MD) was calculated in a region of interest (ROI) in which concussed athletes (n = 82) showed significantly elevated MD acutely after injury (
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