| Popis: |
Cola nitida and Garcinia kola are found and widely consumed in West Africa. The seeds of these plants have various traditional uses and are reported to exhibit several bioactivities. Their phytochemical, antioxidant and antibacterial properties of methanol, ethanol and aqueous extracts were investigated in the present study. Phytochemical screening and quantification of total phenolic contents analysis were carried out for phytochemical investigation. Preliminary phytochemical screening revealed the presence of flavonoids, alkaloids, tannins, saponins, protein and glycosides in the seed extracts. Quantitative phytochemical constituents revealed 0.818 ± 0.021and 0.700 ± 0.017mg of phenolic compounds and total flavonoid content of 25.63 ± 1.60 and 25.10 ± 1.85mg in G. kola and C. nitida respectively. The extracts showed potent antioxidant activities compared to standard antioxidants by significantly inhibiting 2, 2-diphenyl-1-picrylhydrazyl (DPPH), hydroxyl radical (∙OH), and superoxide anion radicals (O2∙) dose dependently. The methanol extracts of G. kola and C. nitida showed significant inhibitory action (p |
