GJA1 promotes hepatocellular carcinoma progression by mediating TGF-β-induced activation and the epithelial–mesenchymal transition of hepatic stellate cells

Autor: Niu Gengming, Zhang Xiaotian, Hong Runqi, Yang Ximin, Gu Jiawei, Song Tao, Hu Zhiqing, Chen Liang, Wang Xin, Xia Jie, Ke Zhongwei, Ren Jun, Hong Liang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Open Medicine, Vol 16, Iss 1, Pp 1459-1471 (2021)
Druh dokumentu: article
ISSN: 2391-5463
DOI: 10.1515/med-2021-0344
Popis: Gap junction protein, alpha 1 (GJA1), which is correlated with recurrences and unfavorable prognoses in hepatocellular carcinomas (HCCs), is one of the specific proteins expressed by activated hepatic stellate cells (HSCs).
Databáze: Directory of Open Access Journals