Autor: |
Søren Christiansen, Steffen Christensen, Lars Pedersen, Henrik Gammelager, J. Bradley Layton, M. Alan Brookhart, Christian Fynbo Christiansen |
Jazyk: |
angličtina |
Rok vydání: |
2017 |
Předmět: |
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Zdroj: |
Critical Care, Vol 21, Iss 1, Pp 1-9 (2017) |
Druh dokumentu: |
article |
ISSN: |
1364-8535 |
DOI: |
10.1186/s13054-017-1903-y |
Popis: |
Abstract Background The optimal time to initiate renal replacement therapy (RRT) in intensive care unit (ICU) patients with acute kidney injury (AKI) is unclear. We examined the impact of early RRT on long-term mortality, risk of chronic kidney disease (CKD), and end-stage renal disease (ESRD). Methods This cohort study included all adult patients treated with continuous RRT in the ICU at Aarhus University Hospital, Skejby, Denmark (2005–2015). Data were obtained from a clinical information system and population-based registries. Early treatment was defined as RRT initiation at AKI stage 2 or below, and late treatment was defined as RRT initiation at AKI stage 3. Inverse probability of treatment (IPT) weights were computed from propensity scores. The IPT-weighted cumulative risk of CKD (estimated glomerular filtration rate |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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