Prognostic impact of upper and lower extremity muscle mass in heart failure

Autor: Masaaki Konishi, Eiichi Akiyama, Yasushi Matsuzawa, Ryosuke Sato, Shinnosuke Kikuchi, Hidefumi Nakahashi, Kozo Okada, Noriaki Iwahashi, Masami Kosuge, Toshiaki Ebina, Kiyoshi Hibi, Toshihiro Misumi, Kouichi Tamura, Kazuo Kimura
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: ESC Heart Failure, Vol 10, Iss 1, Pp 732-737 (2023)
Druh dokumentu: article
ISSN: 2055-5822
DOI: 10.1002/ehf2.14195
Popis: Abstract Aims Reduced skeletal muscle mass is a major component of sarcopenia, associated with impaired exercise capacity and poor prognosis in patients with heart failure (HF). Measurement of skeletal muscle mass by dual‐energy X‐ray absorptiometry may be affected by fluid retention, typically in the patients' lower extremities. The aim of the present study was to elucidate the association between upper and lower extremity skeletal muscle mass (USM and LSM) and all‐cause mortality in hospitalized patients with HF, after discharge. Methods This was a single‐centre observational cohort study of 418 patients (59% were men) admitted with a diagnosis of HF (71 ± 13 years), with a left ventricular ejection fraction of 39 ± 16%. USM and LSM were measured by dual‐energy X‐ray absorptiometry with patients in a stable state after decongestion therapy. Results The USM and LSM were 5.29 ± 1.18 and 13.78 ± 3.20 kg for men and 3.37 ± 0.68 and 9.19 ± 1.80 kg for women. A positive correlation was obtained between USM and LSM with mid‐upper arm circumference (r = 0.684, P
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