Sporadic Creutzfeldt-Jakob Syndrome Misdiagnosed as Recurrent Stroke: A Case Report

Autor: Min Joon Bae, In Hyun Kang, Yang Rok Hur, Ki Hun Hwang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Annals of Geriatric Medicine and Research, Vol 25, Iss 2, Pp 133-136 (2021)
Druh dokumentu: article
ISSN: 2508-4798
2508-4909
DOI: 10.4235/agmr.21.0030
Popis: While sporadic Creutzfeldt-Jakob disease (sCJD) typically presents with neurological symptoms such as cognitive impairment, ataxia, and myoclonus, its clinical manifestations can be diverse. We report a 70-year-old woman with sCJD who was misdiagnosed with recurrent stroke. She initially showed hemiplegia and high-intensity signals on brain diffusion-weighted magnetic resonance imaging (DWI), which corresponded to the symptoms of a stroke. She was diagnosed with recurrent stroke as her muscle weakness showed stepwise deterioration, with the appearance of additional high-intensity signals on brain DWI. Several days later, she developed Broca’s aphasia, cognitive impairment, and myoclonus in the right upper and left lower extremities. Brain DWI showed high-intensity signals in the cortex, caudate nucleus, and putamen. Therefore, sCJD was suspected; she subsequently underwent further evaluation and was diagnosed with sCJD. The findings of this case indicate that sCJD can have a clinical course similar to that of recurrent stroke.
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