Cortical spreading depression in migraine-time to reconsider?

Autor:	Alan J McComas, Adrian R M Upton
Jazyk:	angličtina
Rok vydání:	2015
Předmět:	enxaqueca depressão alastrante estimulação magnética transcraniana Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571
Zdroj:	Arquivos de Neuro-Psiquiatria, Vol 73, Iss 8, Pp 714-721 (2015)
Druh dokumentu:	article
ISSN:	1678-4227 0004-282X
DOI:	10.1590/0004-282X20150094
Popis:	New evidence concerning the pathophysiology of migraine has come from the results of therapeutic transcranial magnetic stimulation (tTMS). The instantaneous responses to single pulses applied during the aura or headache phase, together with a number of other observations, make it unlikely that cortical spreading depression is involved in migraine. tTMS is considered to act by abolishing abnormal impulse activity in cortical pyramidal neurons and a suggestion is made as to how this activity could arise.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0b28803b5caa4ff6b2e7648b87935f3e Zobrazit plný text záznamu View record in DOAJ