Revealing the role of the human blood plasma proteome in obesity using genetic drivers

Autor: Shaza B. Zaghlool, Sapna Sharma, Megan Molnar, Pamela R. Matías-García, Mohamed A. Elhadad, Melanie Waldenberger, Annette Peters, Wolfgang Rathmann, Johannes Graumann, Christian Gieger, Harald Grallert, Karsten Suhre
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-21542-4
Popis: Blood circulating proteins reflect biological processes, thus providing insight into complex traits. Here the authors study the relationship between 1000 plasma proteins and body mass index (BMI), highlighting widespread proteome changes and causal relationships between BMI and specific proteins.
Databáze: Directory of Open Access Journals