Antinociceptive properties of the essential oil of Ocimum gratissimum L. (Labiatae) in mice

Autor: M. Rabelo, E.P. Souza, P.M.G. Soares, A.V. Miranda, F.J.A. Matos, D.N. Criddle
Jazyk: angličtina
Rok vydání: 2003
Předmět:
Zdroj: Brazilian Journal of Medical and Biological Research, Vol 36, Iss 4, Pp 521-524 (2003)
Druh dokumentu: article
ISSN: 0100-879X
1414-431X
DOI: 10.1590/S0100-879X2003000400016
Popis: We have investigated the antinociceptive effects of the essential oil of Ocimum gratissimum L. (Labiatae) (EOOG) in two classical models of pain in male Swiss mice (25-35 g), the writhing test and the formalin test. At doses of 30, 100 and 300 mg/kg (po), EOOG produced a dose-dependent inhibition (from 58.3 ± 4.4 to 40.7 ± 6.3, 36.4 ± 3.6 and 24.6 ± 3.6, respectively; N = 8-10, P
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