Antinociceptive properties of the essential oil of Ocimum gratissimum L. (Labiatae) in mice
Autor: | M. Rabelo, E.P. Souza, P.M.G. Soares, A.V. Miranda, F.J.A. Matos, D.N. Criddle |
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Jazyk: | angličtina |
Rok vydání: | 2003 |
Předmět: | |
Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 36, Iss 4, Pp 521-524 (2003) |
Druh dokumentu: | article |
ISSN: | 0100-879X 1414-431X |
DOI: | 10.1590/S0100-879X2003000400016 |
Popis: | We have investigated the antinociceptive effects of the essential oil of Ocimum gratissimum L. (Labiatae) (EOOG) in two classical models of pain in male Swiss mice (25-35 g), the writhing test and the formalin test. At doses of 30, 100 and 300 mg/kg (po), EOOG produced a dose-dependent inhibition (from 58.3 ± 4.4 to 40.7 ± 6.3, 36.4 ± 3.6 and 24.6 ± 3.6, respectively; N = 8-10, P |
Databáze: | Directory of Open Access Journals |
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