Prognostic Impact of Renal Function on 5‐Year Outcomes After Fractional Flow Reserve‐Guided Deferral of Revascularization

Autor: Ryosuke Itakura, Shoichi Kuramitsu, Jun Kikuchi, Yoshiaki Kawase, Takuya Mizukami, Tomohiro Shinozaki, Kazunori Horie, Hiroaki Takashima, Hidenobu Terai, Yuetsu Kikuta, Takayuki Ishihara, Tatsuya Saigusa, Tomohiro Sakamoto, Nobuhiro Suematsu, Yasutsugu Shiono, Taku Asano, Kenichi Tsujita, Katsuhiko Masamura, Tatsuki Doijiri, Fumitoshi Toyota, Manabu Ogita, Tairo Kurita, Akiko Matsuo, Ken Harada, Kenji Yaginuma, Shinjo Sonoda, Hiroyoshi Yokoi, Nobuhiro Tanaka, Hitoshi Matsuo
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 20 (2023)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.123.030886
Popis: Background Chronic kidney disease (CKD) might influence fractional flow reserve (FFR) value, potentially attenuating its prognostic utility. However, few large‐scale data are available regarding clinical outcomes after FFR‐guided deferral of revascularization in patients with CKD. Methods and Results From the J‐CONFIRM registry (Long‐Term Outcomes of Japanese Patients With Deferral of Coronary Intervention Based on Fractional Flow Reserve in Multicenter Registry), 1218 patients were divided into 3 groups according to renal function: (1) non‐CKD (estimated glomerular filtration rate ≥60 mL/min per 1.73 m2), n=385; (2) CKD (estimated glomerular filtration rate 15–59 mL/min per 1.73 m2, n=763); and (3) end‐stage renal disease (ESRD) (eGFR
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