Modeling Trienzyme Biosensor at Internal Diffusion Limitation

Autor: J. Kulys
Jazyk: angličtina
Rok vydání: 2004
Předmět:
Zdroj: Nonlinear Analysis, Vol 9, Iss 2 (2004)
Druh dokumentu: article
ISSN: 1392-5113
2335-8963
DOI: 10.15388/NA.2004.9.2.15162
Popis: A model of biosensor containing three immobilized enzymes utilizing consecutive substrate conversion in the chain was developed. The modeling was performed at an internal diffusion limitation and a steadystate condition. The calculations showed that significant response of biosensors was produced if diffusion modules were larger than 1 for all enzyme reactions. Due to diffusion limitation the apparent stability of biosensor response increased many times in comparison to stability of the most labile enzyme of the chain.
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