Association between depression and HIV treatment outcomes in a US military population with HIV infection

Autor: Brandon Carney, Colton Daniels, Xiaohe Xu, Thankam Sunil, Anuradha Ganesan, Jason M. Blaylock, Karl C. Kronmann, Christina Schofield, Tahaniyat Lalani, Brian Agan, Jason F. Okulicz
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-6 (2021)
Druh dokumentu: article
ISSN: 1742-6405
DOI: 10.1186/s12981-021-00350-2
Popis: Abstract Background Depression is common among HIV-infected individuals and may contribute to suboptimal adherence to antiretroviral therapy (ART) and subsequent inability to attain viral load (VL) suppression. We evaluated associations between depression, self-reported adherence, and longitudinal HIV treatment outcomes in US Military HIV Natural History Study (NHS) participants with and without depression. Methods Male NHS participants with available ICD-9 data for mental health diagnoses, Center for Epidemiological Studies Depression (CES-D) measures, and self-reported adherence (SRA) were included. ART use was defined as ART initiation between 2006 and 2010, with follow-up through 2015. SRA was defined as taking 95% of ART doses and continuous ART was defined as longitudinal ART use with gaps
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