Thrombotic microangiopathy associated with lenvatinib therapy

Autor: Macarena Contreras Angulo, Belén García Izquierdo, Laura Armengod Grao, Nuria Palacios García
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Endocrine Oncology, Vol 3, Iss 1, Pp 1-5 (2023)
Druh dokumentu: article
ISSN: 2634-4793
DOI: 10.1530/EO-22-0078
Popis: Systemic thrombotic microangiopathy (TMA) is a serious condition whose early treatment is essential to reduce morbidity and mortality. TMA with only renal involvement has been associated with tyrosine kinase inhibitors, including lenvatinib, a drug used for certain advanced neoplasms. To date, TMA with systemic involvement associated with this drug has not been described. We present the case of a patient with progressive metastatic thyroid cancer who developed this complication after starting treatment with lenvatinib. We describe the signs and symptoms that led to the diagnosis and the treatment required for her recovery.
Databáze: Directory of Open Access Journals