Randomized, Blinded Trial Comparing Enoxaparin with Unfractionated Heparin in Patients Undergoing Contemporary Percutaneous Coronary Intervention

Autor: Hosein Vakili, Ali Mir, Mohammad Hasan Namazi, Habibollahe Saadat, Morteza Safi, Mohammad Reza Motamedi, Roxana Sadeghi
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Journal of Tehran University Heart Center, Vol 2, Iss 2 (2007)
Druh dokumentu: article
ISSN: 1735-8620
2008-2371
Popis: Background: This study was designed to examine a unique and low dose use of intravenous enoxaparin in elective percutaneous coronary intervention (PCI) that would be applicable to an unselected population regardless of age, weight, and renal function. There is limited experience in anticoagulation using intravenous low-molecular-weight heparin in PCI. Methods: A total of 100 consecutive patients undergoing elective PCI were treated with a single IV bolus of enoxaparin (0.5mg/kg) in group A of patients (n=50) or with unfractionated heparin in group B of patients (n=50). Sheaths were removed immediately after the procedure in patients treated with enoxaparin and some hours later in those treated with unfractionated heparin. Results: In group A, ACT was 124.6±9.3 before PCI and 149.2±17.1 after that (P
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