| Autor: |
Malgorzata Kubiak, Mark Ditzel |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Journal of Developmental Biology, Vol 4, Iss 3, p 25 (2016) |
| Druh dokumentu: |
article |
| ISSN: |
2221-3759 |
| DOI: |
10.3390/jdb4030025 |
| Popis: |
This review highlights the essential role of Hedgehog (Hh) signalling in the developmental steps of temporomandibular joint (TMJ) formation. We review evidence for intra- and potentially inter-tissue Hh signaling as well as Glioma-Associated Oncogene Homolog (GLI) dependent and independent functions. Morphogenesis and maturation of the TMJ’s individual components and the general landscape of Hh signalling is also covered. Comparison of the appendicular knee and axial TMJ also reveals interesting differences and similarities in their mechanisms of development, chondrogenesis and reliance on Hh signalling. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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