Predictive value of preoperative liver function for perioperative massive blood transfusion in patients undergoing ascending aorta surgery

Autor: Lihui QIAN, Caimin ZHU, Zhangsheng ZHAO, Lei WANG, Wei ZHOU, Qile XIN, Youli MA, Qitian MU
Jazyk: čínština
Rok vydání: 2023
Předmět:
Zdroj: Zhongguo shuxue zazhi, Vol 36, Iss 12, Pp 1118-1123 (2023)
Druh dokumentu: article
ISSN: 1004-549X
1004-549x
DOI: 10.13303/j.cjbt.issn.1004-549x.2023.12.009&lang=en
Popis: Objective To explore the predictive value of preoperative liver function for massive blood transfusion (MBT) in patients undergoing ascending aorta surgery. Methods Data from 238 patients undergoing ascending aorta surgery in the Department of Cardiovascular Surgery at The Affiliated Lihuili Hospital of Ningbo University were collected. Preoperative liver function tests were performed for all patients. Based on the perioperative transfusion volumes of red blood cell suspension, patients were divided into the MBT group, non-MBT group, and no blood transfusion (NBT) group. Clinical data during the perioperative period were compared among different groups. Receiver operating characteristic curve (ROC curve) analysis was used to assess the predictive value of liver function indicators for MBT and determine cut-off values. Results Compared with the non-MBT group and NBT group, the MBT group showed statistically significant differences in preoperative levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), direct bilirubin (DBIL), and serum albumin (SA) (P28.50 U/L, ALT >40.00 U/L, SA ≤34.55 g/L, and DBIL >4.25 μmol/L, there was a significant increase in the transfusion volume of various blood components and the incidence of MBT. Conclusion Preoperative liver function indicators (AST, ALT, SA, DBIL) have a moderate predictive value for MBT in patients undergoing ascending aorta surgery.
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