Methods to investigate the structure and connectivity of the nervous system

Autor:	Donghyung Lee, Ting-Hao Huang, Aubrie De La Cruz, Antuca Callejas, Carlos Lois
Jazyk:	angličtina
Rok vydání:	2017
Předmět:	brain circuit connectomics neuron synapse wiring diagram Biology (General) QH301-705.5
Zdroj:	Fly, Vol 11, Iss 3, Pp 224-238 (2017)
Druh dokumentu:	article
ISSN:	1933-6934 1933-6942 19336934
DOI:	10.1080/19336934.2017.1295189
Popis:	Understanding the computations that take place in neural circuits requires identifying how neurons in those circuits are connected to one another. In addition, recent research indicates that aberrant neuronal wiring may be the cause of several neurodevelopmental disorders, further emphasizing the importance of identifying the wiring diagrams of brain circuits. To address this issue, several new approaches have been recently developed. In this review, we describe several methods that are currently available to investigate the structure and connectivity of the brain, and discuss their strengths and limitations.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0aa2110edcc24d6388c561ca99de4cf9 Zobrazit plný text záznamu View record in DOAJ