Dynamic changes in quality of life in older patients with chronic obstructive pulmonary disease: a 7-year follow up

Autor:	Chun-Hsiang Yu, Sheng-Han Tsai, Jo-Ying Hung, Pei-Fang Su, Chih-Hui Hsu, Xin-Min Liao, Tzuen-Ren Hsiue, Chiung-Zuei Chen
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Chronic obstructive pulmonary disease Quality of life Dynamic change. Computer applications to medicine. Medical informatics R858-859.7
Zdroj:	Health and Quality of Life Outcomes, Vol 22, Iss 1, Pp 1-10 (2024)
Druh dokumentu:	article
ISSN:	1477-7525
DOI:	10.1186/s12955-024-02296-1
Popis:	Abstract Purposes : Chronic obstructive pulmonary disease (COPD) is a major cause of the rapid decline of health-related quality of life (HRQoL), associated with accelerated frailty in older populations. This study aimed to analyse the long-term dynamic changes of HRQoL and the predictive factors for the rapid decline of HRQoL in older patients with COPD. Methods Overall 244 patients with COPD, aged ≧ 65 years from one medical centre were enrolled between March 2012 and July 2020. Further, we prospectively assessed HRQoL scores with utility values, using EuroQol Five-Dimension (EQ-5D) questionnaires. Additionally, long-term dynamic changes in HRQoL were analysed using the Kernel smoothing method and examined the factors contributing to the deterioration of HRQoL using a linear mixed effects model. Results Older patients with COPD with forced expiration volume (FEV1)
Databáze:	Directory of Open Access Journals
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