Clinical characteristics and outcome of COVID-19 patients with Parkinson’s disease: a hospital-based case–control study in Shanghai, China

Autor: Li Wu, Jun Shen, Yuhan Jiang, Xiaolei Shen, Ping Wang, Xin Nie, Wenyan Kang, Jianren Liu, Wei Chen
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Aging Neuroscience, Vol 15 (2023)
Druh dokumentu: article
ISSN: 1663-4365
DOI: 10.3389/fnagi.2023.1138418
Popis: BackgroundClinical manifestations of Parkinson’s disease (PD) after Corona Virus Disease 2019 (COVID-19) infection are poorly investigated.ObjectiveWe aimed to explore the clinical features and outcomes of hospitalized PD patients with COVID-19.MethodsA total of 48 PD patients and 96 age-and sex-matched non-PD patients were included. Demographics, clinical characteristics and outcomes were compared between two groups.ResultsPD patients with COVID-19 were elderly (76.69 ± 9.21 years) with advanced stage (H-Y stage 3–5 as 65.3%). They had less clinical symptoms (nasal obstruction, etc.), more proportions of severe/critical COVID-19 clinical classification (22.9 vs. 1.0%, p
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