Intracranial hemorrhage and Covid-19: A retrospective analysis of 1675 hospitalized Covid-19 Brazilian patients

Autor: Artur Eduardo Martio, Pedro de Moraes Rêgo Soares, Octávio Ruschel Karam, Wagner Lazaretto Padua, Luciano Bambini Manzato, Paulo Moacir Mesquita Filho
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Brain Hemorrhages, Vol 4, Iss 2, Pp 57-64 (2023)
Druh dokumentu: article
ISSN: 2589-238X
DOI: 10.1016/j.hest.2023.01.002
Popis: Objective: The present study seeks to overcome the lack of data on Covid-19 associated intracranial hemorrhage (ICH) in Brazil. Methods: This is a retrospective, single-center case series of consecutive patients. It is a subanalysis of a larger study still in progress, which covers all neurological manifestations that occurred in patients admitted between March 1st, 2020 and June 1st, 2022, with active SARS-CoV-2 infection confirmed by polymerase chain reaction test. All patients with non-traumatic ICH were included. Results: A total of 1675 patients were evaluated: 917 (54.75 %) had one or more neurological symptoms and 19 had non-traumatic ICH, comprising an incidence of 1.13 %. All patients had one or more risk factors for ICH. The presence of neurological manifestations before the ICH and ICU admission showed a statistically significant relationship with the occurrence of ICH (X2 = 6.734, p = 0.0095; OR = 4.47; CI = 1.3–15.4; and FET = 9.13; p =
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