Inhibition of polar actin assembly by astral microtubules is required for cytokinesis

Autor: Anan Chen, Luisa Ulloa Severino, Thomas C. Panagiotou, Trevor F. Moraes, Darren A. Yuen, Brigitte D. Lavoie, Andrew Wilde
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-22677-0
Popis: During cell division, the actin cytoskeletal network at both the equatorial contractile ring and cell cortex are known to play a role, but the regulation of γ-actin during cytokinesis is less well understood. Here, the authors show that recruitment of β-actin to the contractile ring and loss of γ-actin from the cell poles is required for completion of cell division.
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