Autor: |
Felix Gerber, Ravi Gupta, Thabo Ishmael Lejone, Thesar Tahirsylaj, Tristan Lee, Giuliana Sanchez-Samaniego, Maurus Kohler, Maria-Inés Haldemann, Fabian Raeber, Mamakhala Chitja, Malebona Mathulise, Thuso Kabi, Mosoetsi Mokaeane, Malehloa Maphenchane, Manthabiseng Molulela, Makhebe Khomolishoele, Mota Mota, Sesale Masike, Matumaole Bane, Mamoronts’ane Pauline Sematle, Retselisitsoe Makabateng, Madavida Mphunyane, Sejojo Phaaroe, Dave Brian Basler, Kevin Kindler, Thilo Burkard, Matthias Briel, Frédérique Chammartin, Niklaus Daniel Labhardt, Alain Amstutz |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Trials, Vol 25, Iss 1, Pp 1-11 (2024) |
Druh dokumentu: |
article |
ISSN: |
1745-6215 |
DOI: |
10.1186/s13063-024-08226-2 |
Popis: |
Abstract Background Arterial hypertension (aHT) is a major cause for premature morbidity and mortality. Control rates remain poor, especially in low- and middle-income countries. Task-shifting to lay village health workers (VHWs) and the use of digital clinical decision support systems may help to overcome the current aHT care cascade gaps. However, evidence on the effectiveness of comprehensive VHW-led aHT care models, in which VHWs provide antihypertensive drug treatment and manage cardiovascular risk factors is scarce. Methods Using the trials within the cohort (TwiCs) design, we are assessing the effectiveness of VHW-led aHT and cardiovascular risk management in two 1:1 cluster-randomized trials nested within the Community-Based chronic disease Care Lesotho (ComBaCaL) cohort study (NCT05596773). The ComBaCaL cohort study is maintained by trained VHWs and includes the consenting inhabitants of 103 randomly selected villages in rural Lesotho. After community-based aHT screening, adult, non-pregnant ComBaCaL cohort participants with uncontrolled aHT (blood pressure (BP) ≥ 140/90 mmHg) are enrolled in the aHT TwiC 1 and those with controlled aHT (BP |
Databáze: |
Directory of Open Access Journals |
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