Deltamethrin interacts with Culex quinquefasciatus odorant-binding protein: a novel potential resistance mechanism

Autor: Rui-xin Shen, Yi-ting Wang, Jia-hong Wu, Ning Zhang, Heng-duan Zhang, Dan Xing, Yan Chen, Chun-xiao Li, Tong-yan Zhao
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Parasites & Vectors, Vol 15, Iss 1, Pp 1-9 (2022)
Druh dokumentu: article
ISSN: 1756-3305
DOI: 10.1186/s13071-021-05041-5
Popis: Highlights 1. RNA sequencing showed that OBP28 gene expression was higher in the deltamethrin-resistant strains. 2. The qPCR results verified that OBP28 gene expression was higher in the resistant strains. 3. RNA interference silenced the OBP28 gene at an efficiency of more than 50%. 4. The sensitivity of Cx. quinquefasciatus to deltamethrin increased after OBP28 had been silenced.
Databáze: Directory of Open Access Journals
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