Immune and hormonal activity in adults suffering from depression
| Autor: | S.O.V. Nunes, E.M.V. Reiche, H.K. Morimoto, T. Matsuo, E.N. Itano, E.C.D. Xavier, C.M. Yamashita, V.R. Vieira, A.V. Menoli, S.S. Silva, F.B. Costa, F.V. Reiche, F.L.V. Silva, M.S. Kaminami |
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| Jazyk: | angličtina |
| Rok vydání: | 2002 |
| Předmět: | |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 35, Iss 5, Pp 581-587 (2002) |
| Druh dokumentu: | article |
| ISSN: | 0100-879X 1414-431X |
| DOI: | 10.1590/S0100-879X2002000500011 |
| Popis: | An association between depression and altered immune and hormonal systems has been suggested by the results of many studies. In the present study we carried out immune and hormonal measurements in 40 non-medicated, ambulatory adult patients with depression determined by CID-10 criteria and compared with 34 healthy nondepressed subjects. The severity of the condition was determined with the Hamilton Depression Rating Scale. Of 40 depressed patients, 31 had very severe and 9 severe or moderate depression, 29 (72.5%) were females and 11 (27.5%) were males (2.6:1 ratio). The results revealed a significant reduction of albumin and elevation of alpha-1, alpha-2 and ß-globulins, and soluble IL-2 receptor in patients with depression compared to the values obtained for nondepressed subjects (P |
| Databáze: | Directory of Open Access Journals |
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