IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers

Autor:	Figen Aydin, Ahmet Kaya, Levent Karapinar, Mert Kumbaraci, Ahmet Imerci, Hasan Karapinar, Cengiz Karakuzu, Mustafa Incesu
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Journal of Diabetes Research, Vol 2013 (2013)
Druh dokumentu:	article
ISSN:	2314-6745 2314-6753
DOI:	10.1155/2013/567834
Popis:	Objectives. To investigate insulin-like growth factor I (IGF-1) levels in response to hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers and to determine whether IGF-1 is a predictive indicator of wound healing in patients with diabetic foot ulcers. Design and Methods. We treated 48 consecutive patients with diabetic foot ulcers with HBOT. Alterations of IGF-1 levels in patients whose wound healed with HBOT were compared with those in patients who did not benefit from HBOT. Results. There was no significant difference in initial IGF-1 levels between the two groups (P=0.399). The mean IGF-1 level increased with HBOT (P
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/aa0a10d0e57f4ace837628ad60feb81b Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF