IGF-1 Increases with Hyperbaric Oxygen Therapy and Promotes Wound Healing in Diabetic Foot Ulcers
Autor: | Figen Aydin, Ahmet Kaya, Levent Karapinar, Mert Kumbaraci, Ahmet Imerci, Hasan Karapinar, Cengiz Karakuzu, Mustafa Incesu |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2013 |
Předmět: | |
Zdroj: | Journal of Diabetes Research, Vol 2013 (2013) |
Druh dokumentu: | article |
ISSN: | 2314-6745 2314-6753 |
DOI: | 10.1155/2013/567834 |
Popis: | Objectives. To investigate insulin-like growth factor I (IGF-1) levels in response to hyperbaric oxygen therapy (HBOT) for diabetic foot ulcers and to determine whether IGF-1 is a predictive indicator of wound healing in patients with diabetic foot ulcers. Design and Methods. We treated 48 consecutive patients with diabetic foot ulcers with HBOT. Alterations of IGF-1 levels in patients whose wound healed with HBOT were compared with those in patients who did not benefit from HBOT. Results. There was no significant difference in initial IGF-1 levels between the two groups (P=0.399). The mean IGF-1 level increased with HBOT (P |
Databáze: | Directory of Open Access Journals |
Externí odkaz: |