Characteristics of Hepatitis B Infection in a Sample of Omani Patients

Autor: Khalid Al-Naamani, Ali Al-Maqbali, Siham Al-Sinani
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Sultan Qaboos University Medical Journal, Vol 13, Iss 3, Pp 380-385 (2013)
Druh dokumentu: article
ISSN: 2075-051X
2075-0528
Popis: Objectives: This study aimed to describe the demographic and virological characteristics of chronic hepatitis B virus (HBV) infection in a sample of Omani patients, and indirectly assess the efficacy of hepatitis B vaccination programmes and catch-up strategies. Methods: A retrospective study was undertaken of all patients with chronic HBV infections evaluated and followed-up at the Hepatology Clinic of the Armed Forces Hospital (AFH), Muscat, Oman, between January 2009 and April 2011. Results: A total of 154 patients met the inclusion criteria. The mean age of infected patients was 33 years with 72.7% being over 27 years. Females constituted 47.7% of the patients. Half of the cohort was referred either from the AFH’s Obstetric Clinic (29.2%) or its Blood Bank (22.1%). A family history of chronic HBV infection was present in 70% of patients. A total of 95% had positive hepatitis B surface antigens, while only 5% had isolated total hepatitis B core antibodies. Most patients (96%) were hepatitis B e-antigen-negative. The majority (77.9%) had low HBV dioribonucleic acid levels of
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