Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

Autor: Amy M. Buckley, Margaret R. Dunne, Maria E. Morrissey, Susan A. Kennedy, Aoife Nolan, Maria Davern, Emma K. Foley, Niamh Clarke, Joanne Lysaght, Narayanasamy Ravi, Dermot O’Toole, Finbar MacCarthy, John V. Reynolds, Breandán N. Kennedy, Jacintha O’Sullivan
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-020-68777-7
Popis: Abstract Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survival rates remain at
Databáze: Directory of Open Access Journals
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