| Autor: |
Aswini Krishnan, Jean Berthelet, Emilie Renaud, Sebastian Rosigkeit, Ute Distler, Eric Stawiski, Jing Wang, Zora Modrusan, Marc Fiedler, Mariann Bienz, Stefan Tenzer, Arno Schad, Wilfried Roth, Bernd Thiede, Somasekar Seshagiri, Thomas J. Musholt, Krishnaraj Rajalingam |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-020-15955-w |
| Popis: |
Papillary thyroid cancer (PTC) is one of the most common type of endocrine malignancy. Here, the authors use proteogenomic approaches to analyse the primary tumour and lymph node metastases from a PTC patient and report an oncogenic RET fusion, and potential druggable targets from the ubiquitin signaling machinery for treating human PTCs. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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