| Autor: |
David W Eyre, Sheila F Lumley, Denise O'Donnell, Mark Campbell, Elizabeth Sims, Elaine Lawson, Fiona Warren, Tim James, Stuart Cox, Alison Howarth, George Doherty, Stephanie B Hatch, James Kavanagh, Kevin K Chau, Philip W Fowler, Jeremy Swann, Denis Volk, Fan Yang-Turner, Nicole Stoesser, Philippa C Matthews, Maria Dudareva, Timothy Davies, Robert H Shaw, Leon Peto, Louise O Downs, Alexander Vogt, Ali Amini, Bernadette C Young, Philip George Drennan, Alexander J Mentzer, Donal T Skelly, Fredrik Karpe, Matt J Neville, Monique Andersson, Andrew J Brent, Nicola Jones, Lucas Martins Ferreira, Thomas Christott, Brian D Marsden, Sarah Hoosdally, Richard Cornall, Derrick W Crook, David I Stuart, Gavin Screaton, Oxford University Hospitals Staff Testing Group, Timothy EA Peto, Bruno Holthof, Anne-Marie O'Donnell, Daniel Ebner, Christopher P Conlon, Katie Jeffery, Timothy M Walker |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
eLife, Vol 9 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2050-084X |
| DOI: |
10.7554/eLife.60675 |
| Popis: |
We conducted voluntary Covid-19 testing programmes for symptomatic and asymptomatic staff at a UK teaching hospital using naso-/oro-pharyngeal PCR testing and immunoassays for IgG antibodies. 1128/10,034 (11.2%) staff had evidence of Covid-19 at some time. Using questionnaire data provided on potential risk-factors, staff with a confirmed household contact were at greatest risk (adjusted odds ratio [aOR] 4.82 [95%CI 3.45–6.72]). Higher rates of Covid-19 were seen in staff working in Covid-19-facing areas (22.6% vs. 8.6% elsewhere) (aOR 2.47 [1.99–3.08]). Controlling for Covid-19-facing status, risks were heterogenous across the hospital, with higher rates in acute medicine (1.52 [1.07–2.16]) and sporadic outbreaks in areas with few or no Covid-19 patients. Covid-19 intensive care unit staff were relatively protected (0.44 [0.28–0.69]), likely by a bundle of PPE-related measures. Positive results were more likely in Black (1.66 [1.25–2.21]) and Asian (1.51 [1.28–1.77]) staff, independent of role or working location, and in porters and cleaners (2.06 [1.34–3.15]). |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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