Chronic skin ulcers in hemodialysis patient: A fatal case of calciphylaxis

Autor: Jawad Shabani, MD, Vaibhav Shah, DO, Vikash Jaiswal, MD, Akanksha Sharma, MD, David Song, DO
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Radiology Case Reports, Vol 18, Iss 4, Pp 1522-1526 (2023)
Druh dokumentu: article
ISSN: 1930-0433
DOI: 10.1016/j.radcr.2023.01.053
Popis: Calciphylaxis is a rare and deadly vascular disease with poorly understood pathophysiology and without definitive treatment. Early presentations include skin ulcers with risk factors including end stage renal disease on hemodialysis, hypertension, hyperlipidemia, and diabetes mellitus. In our case, we present an 80-year-old female with multiple risk factors including hemodialysis and clinical features of necrotic and gangrenous skin lesions diagnostic of calciphylaxis who became hemodynamically unstable and ultimately expired secondary to toxic sequelae. We illustrate this case to explore early clinical presentation, limitations of current disease management and treatments, and the role for further studies to improve diagnosis and reduce mortality.
Databáze: Directory of Open Access Journals