Phytochemical characterization and multifaceted bioactivity assessment of essential oil from Clinopodium nepeta subsp. ascendens: potential for the food and pharmaceutical sectors
| Autor: | Mohamed Taibi, Amine Elbouzidi, Mounir Haddou, Yousra Belbachir, Abdellah Baraich, Zineb Khalil, Reda Bellaouchi, Abdeslam Asehraou, Mohamed Addi, Ammar AL-Farga, Saleh M. Al-Maaqar, Bouchra El Guerrouj, Khalid Chaabane |
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| Jazyk: | English<br />Spanish; Castilian |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | CyTA - Journal of Food, Vol 22, Iss 1 (2024) |
| Druh dokumentu: | article |
| ISSN: | 19476337 1947-6345 1947-6337 |
| DOI: | 10.1080/19476337.2024.2348735 |
| Popis: | ABSTRACTThis study delves into the biological characteristics of Clinopodium nepeta subsp. ascendens (CNEO) essential oil, an indigenous subspecies of eastern Morocco. Distinguished by its purple or pale pinkish-white flowers, CNEO was subjected to thorough phytochemical analysis via gas chromatography-mass spectrometry (GC-MS), revealing 21 terpene compounds, notably Dihydrocarvone (22.70%), Neoisomenthol (43.59%), and Pulegone (20.55%). These compounds, recognized for their biological and pharmacological attributes, were further investigated for their potential applications. Notably, CNEO exhibited dose-dependent anti-inflammatory effects by attenuating nitric oxide (NO) and prostaglandin E2 (PGE2) production. Moreover, it demonstrated promising anticancer activity against MDA-MB-468, HepG2, and HCT-15 cancer cell lines, rivaling doxorubicin’s effectiveness. These findings underscore CNEO’s nutraceutical potential, particularly in food science and industry, suggesting its use as a functional food additive with both nutritional and health benefits |
| Databáze: | Directory of Open Access Journals |
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