Correlation of Aquaporin 3 Expression with the Clinicopathologic Characteristics of Non-small Cell Lung Cancer

Autor: Bailing LI, Lei JIN, Keng ZHONG, Dahai DU
Jazyk: čínština
Rok vydání: 2012
Předmět:
Zdroj: Chinese Journal of Lung Cancer, Vol 15, Iss 7, Pp 404-408 (2012)
Druh dokumentu: article
ISSN: 1009-3419
1999-6187
DOI: 10.3779/j.issn.1009-3419.2012.07.03
Popis: Background and objective Lung cancer is a major health problem worldwide. The aim of this study is to investigate aquaporin 3 (AQP3) expression and its relationship with the clinicopathologic characteristics of non-small cell lung cancer (NSCLC). Methods AQP3 expression and the microvascular density (MVD) of tissue samples from 180 cases with NSCLC were detected by immunohistochemistry. Results AQP3 expression was negative in 25 (13.9%), positive in 67 (37.2%), and strongly positive in 88 (48.9%) of the 180 cases, which was significantly higher than that in the normal tissue (P
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