Medication‐related osteonecrosis of the jaw leading to sepsis in a patient with rheumatoid arthritis: A case report and clinical implications

Autor:	Kazuhiko Iwasaki, Akihito Okazaki
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	abatacept bisphosphonate jaw osteonecrosis sepsis Medicine Medicine (General) R5-920
Zdroj:	Clinical Case Reports, Vol 11, Iss 6, Pp n/a-n/a (2023)
Druh dokumentu:	article
ISSN:	2050-0904
DOI:	10.1002/ccr3.7588
Popis:	Key Clinical Message Chronic use of bisphosphonates, in combination with immunosuppressive therapy, increases the risk of jaw osteonecrosis. When sepsis occurs in patients receiving bisphosphonate, osteonecrosis of the jaw should be considered a potential source of infection. Abstract Reports of medication‐related osteonecrosis of the jaw (MRONJ) accompanied by sepsis are limited. A 75‐year‐old female patient with rheumatoid arthritis, receiving treatment with bisphosphonate and abatacept, developed sepsis secondary to MRONJ. When sepsis occurs in patients receiving bisphosphonate, osteonecrosis of the jaw should be considered a potential source of infection.
Databáze:	Directory of Open Access Journals
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