| Autor: |
Linda Zh. Nikoshvili, Elena P. Tupikina, Lioubov Kiwi-Minsker |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Chemical Engineering Transactions, Vol 88 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2283-9216 |
| DOI: |
10.3303/CET2188045 |
| Popis: |
In this work, the effect of reaction conditions (temperature and composition of the reaction mixture) on the Cu-free Sonogashira cross-coupling of 4-iodoanisole (IAn) and phenylacethylene using nanoparticulate ligandless palladium catalyst based on hyper-cross-linked aromatic polymer (HAP) was studied. Main idea of the study is the ability of HAP to stabilize small Pd nanoparticles that allows developing effective catalysts. It was shown that > 99 % conversion of IAn can be achieved in the presence of Pd/HAP for 1 h at 90 ?? at the absence of amines and copper while using DMSO as a medium. DMSO allowed high solubility of all the reaction components and likely played a role of ligand in the Sonogashira reaction cycle. After the reaction, the cross-coupling product (1-methoxy-4-(phenylethynyl)benzene) was purified, its structure was confirmed by NMR. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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