Low diastolic blood pressure and adverse outcomes in inpatients with acute exacerbation of chronic obstructive pulmonary disease: A multicenter cohort study
| Autor: | Chen Zhou, Qun Yi, Yuanming Luo, Hailong Wei, Huiqing Ge, Huiguo Liu, Xianhua Li, Jianchu Zhang, Pinhua Pan, Mengqiu Yi, Lina Cheng, Liang Liu, Jiarui Zhang, Lige Peng, Adila Aili, Yu Liu, Jiaqi Pu, Haixia Zhou, Xiangxiang Pan, Peifang Wei |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Chinese Medical Journal, Vol 136, Iss 8, Pp 941-950 (2023) |
| Druh dokumentu: | article |
| ISSN: | 0366-6999 2542-5641 00000000 |
| DOI: | 10.1097/CM9.0000000000002666 |
| Popis: | Abstract. Background:. Although intensively studied in patients with cardiovascular diseases (CVDs), the prognostic value of diastolic blood pressure (DBP) has little been elucidated in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This study aimed to reveal the prognostic value of DBP in AECOPD patients. Methods:. Inpatients with AECOPD were prospectively enrolled from 10 medical centers in China between September 2017 and July 2021. DBP was measured on admission. The primary outcome was all-cause in-hospital mortality; invasive mechanical ventilation and intensive care unit (ICU) admission were secondary outcomes. Least absolute shrinkage and selection operator (LASSO) and multivariable Cox regressions were used to identify independent prognostic factors and calculate the hazard ratio (HR) and 95% confidence interval (CI) for adverse outcomes. Results:. Among 13,633 included patients with AECOPD, 197 (1.45%) died during their hospital stay. Multivariable Cox regression analysis showed that low DBP on admission ( |
| Databáze: | Directory of Open Access Journals |
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